Acid Sensing Ion Channels

A family of proton-gated sodium channels that are primarily expressed in neuronal tissue. They are AMILORIDE-sensitive and are implicated in the signaling of a variety of neurological stimuli, most notably that of pain in response to acidic conditions.

Also Known As:

ASIC Channel; Acid-Sensing Ion Channels; Channel, Acid-Sensing Ion; Channel, Proton-Gated Sodium; Ion Channel, Acid-Sensing; Proton Gated Sodium Channel; Proton Gated Sodium Channels; Sodium Channel, Proton-Gated; Sodium Channels, Proton-Gated; Acid Sensing Ion Channel; Acid-Sensing Ion Channel; Proton-Gated Sodium Channel; Proton-Gated Sodium Channels

Amino Acids, Peptides, and Proteins: 1
- Proteins: 484843
  - Carrier Proteins: 12999
    - Membrane Transport Proteins: 589
      - Ion Channels: 6731
        Sodium Channels: 2798
        Acid Sensing Ion Channels: 538
  - Membrane Proteins: 10078
    - Membrane Glycoproteins: 2252
      - Ion Channels: 6731
        Sodium Channels: 2798
        Acid Sensing Ion Channels: 538
    - Membrane Transport Proteins: 589
      - Ion Channels: 6731
        Sodium Channels: 2798
        Acid Sensing Ion Channels: 538
  - Nerve Tissue Proteins: 2
    - Acid Sensing Ion Channels: 538

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Disease

Drug/Important Bio-Agent (IBA)